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HIPEC maximizes intraoperative drug exposure under hyperthermia, but it is typically delivered as a single-session bolus and its benefit can be sensitive to procedural heterogeneity and patient selection

Preclinical studies demonstrate that tirzepatide promotes healthy adipose tissue expansion (hyperplasia rather than hypertrophy), increases adiponectin secretion, and enhances lipid uptake into adipocytes effectively improving the "metabolic sink" function of fat tissue

Supplemental Material 1) for 3 days before and for the 9-day duration of the study

Lycopene: A powerful carotenoid found in red fruits that protects the skin from sun damage and improves skin texture

This review emphasizes three novel nutraceutical modulators such as alpha-lipoic acid (ALA), urolithin A (UA), ergothioneine (EGT), and their respective functions in the regulation of ferroptosis, mitochondrial quality control, and cardiac bioenergetics

The supernatant was separated, evaporated to dryness using a centrifugal vacuum concentrator at 45 C for 60 min, and the residue reconstituted in 100 L of mobile phase