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Managing these involves dose adjustments, supportive care, or temporary discontinuation if needed

Morphological changes of reactive astrocytes have long been recognised not only after traumatic injuries but also in many other pathological contexts

In 1980, during the pioneering analysis of the human lymphocyte surface, Reinherz and Schlossman discovered CD38, a 45-kDa peptide chain consisting of intracellular, transmembrane, and extracellular domains with two to four N-linked oligosaccharide chains of sialic acid residues [4]

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