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Arteriosclerosis, thrombosis, and vascular biology, 2021

New England Journal of Medicine, 384 (11), 9891002.

Intraindividual normalization of the main agalactosylated glycan (FA2) of IgG1 vs FA2-IgG2 was used to distinguish IIM-ILD from IIM-nonILD, which showed that the area under the curve (AUC) of this standard was 88 6%

For the first, transfer occurs through non-contact mechanisms such as cell-free mitochondria (Stephens et al, 2020

In a head-to-head open-label trial reported in February 2026, average weight loss at 84 weeks favored tirzepatide, and the sponsor noted CagriSema did not meet its prespecified non-inferiority target against tirzepatide