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Lastly, the International Restless Leg Syndrome Study Group rating scale (IRLSS) appraises the presence and severity of RLS and is a valuable tool specifically in patients with primary biliary cholangitis (31, 33, 36)

These effects occur when co-extracted compounds from the complex fish tissue matrix interfere with the ionization efficiency of metabolites during mass spectrometry analysis

doi: 10.3390/metabo8040090 270 ChiabrandoDVinchiFFioritoVMercurioSTolosanoE

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T2DM and T2DM-CKD patients exhibit increased gut microbiota TMA-producing bacteria and significantly higher serum TMAO, positively correlating with zonulin, LPS, inflammation, and endothelial dysfunction biomarkers (148)

Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease