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Acetylcholinesterase inhibitors as Alzheimer therapy: from nerve toxins to neuroprotection

Most peer-reviewed research literature studies the copper-bound form because GHK has high affinity for Cu(II) and the copper-bound complex is the bioactive form characterized in cellular research

Despite extensive research into main hallmarks and molecular pathways of cell death in AD, many degenerative processes cannot be explained by these mechanisms alone, resulting in failure of over 200 AD drugs trials aiming at these targets over the past decade (Yiannopoulou et al., 2019)

Springer, Cham Lennicke C, Cochem HM (2021) Redox metabolism: ROS as specific molecular regulators of cell signaling and function

doi:10.2147/CCID.S68424 6

In 1989, homemade garlic oil was linked with several cases of botulism, a rare but severe infection caused by the toxin Clostridium botulinum