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Initially, HDACs are generally believed to preferentially target histones, whereas sirtuins exhibit a notable preference for non-histone components in the cytoplasm or within the nucleus, exhibiting complementary functions [51, 52]

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Chen et al., developed glucose-modified quercetin liposomes (QU-Glu-Lip) to improve the poor solubility, bioavailability, and brain delivery of quercetin

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Additionally, the delayed gastric emptying caused by Zepbound may affect the absorption of oral medications, so patients should discuss appropriate timing of all medications with their healthcare provider