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10.1016/j.yjmcc.2011.10.011 52 LeeJ.LimJ

Moreover, the intervention significantly reduced Falls Efficacy Scale scores and exhibited a trend toward decreased fall incidence, thereby improving postural balance, lower-limb neuromuscular function, and motor confidence, ultimately reducing fall risk in this population (Thiel et al., 2025)

Both activation of PPAR by FAs and peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1) as well as increased PPAR expression increase the binding of PPAR to PPAR response elements on promoters of genes encoding for proteins involved in FA uptake and oxidation, including carnitine palmitoyltransferase 1 (CPT1) and long chain acyl-CoA dehydrogenase (LCAD) as key enzymes of FAO [30]

The adenosine moiety binds down into a hydrophobic pocket, with the ribose phosphate groups pointing outside towards the GTP allosteric site

10.1016/j.jneuroim.2015.05.019 56 DeshmukhV

10.1186/1752-0509-4-139 46 SmithA