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Astrocytic autophagy plasticityboosting degradation of pathological proteins Neurons exposed to -amyloid oligomers fail to cope with this proteotoxic stress, leading to a reduction in the expression of autophagy-related genes (MAP1LC3B/LC3B and SQSTM1/p62, two key autophagy-related genes) alongside a decrease in microtubule-associated protein 2 (MAP2)

Table 3 Actionable research priorities and proposed interventions for advancing Parkinsons disease treatment

Funding This work was funded by the Yunnan University Undergraduate Innovation Fund, S202410673138, Yunnan University Medical Research Foundation Department of Radiology, YDYXJJ20250024, Yunnan University Graduate Research Innovation Fund, KC-252512222

The oncogenic properties of copper involve multiple interconnected mechanisms: (1) activation of LOX-mediated collagen deposition, driving OSF progression (36)

While some early studies suggested DSIP might influence sleep patterns, the research has been inconsistent

Ridlon JM, Harris SC, Bhowmik S, Kang DJ, Hylemon PB (2016a) Consequences of bile salt biotransformations by intestinal bacteria