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Although no difference was detected between DCr and CrO+D animals, this was the first study to compare Hcy levels after applying different protocols of creatine supplementation

Similarly, in a study [54], where mice were sensitized to toluene 2.4-diisocyanate (TDI), replicating a model of AR, oral administration of quercetin for 5 and 7 days, but not 2 and 3 days, could inhibit sneezing and nasal rubbing movements, which were increased by TDI nasal challenge

More refined studies (ATAC-seq, ChIP-seq H3K27ac) map activated enhancers and involved transcription factors (CREB, MEF2)

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The precise mechanisms linking the presence of diabetes to the development of the biological phenomenon of ferroptosis at the renal level remain to be elucidated