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We have thus proposed that SNX2a modulates the activity of SNX1 by altering the conformation or membrane interaction dynamics of the heterodimer, thereby fine-tuning the curvature generation process

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J Pharmacol Exp Ther 268 : 12611270 DeLeve LD, McCuskey RS, Wang X, Hu L, McCuskey MK, Epstein RB, Kanel GC (1999) Characterization of a reproducible rat model of hepatic veno-occlusive disease

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However, despite these trials, BPC-157 lacks FDA approval, raising concerns about its safety and efficacy due to insufficient clinical testing