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The goal is commonly better tissue tolerance, not an overnight reset

Endocr Rev 2003

Unlike apoptosis and necrosis, ferroptosis is characterized by an iron-dependent cell death pattern accompanied by lipid peroxidation ( In this study, we found that GSTT1 and GSTM1 were downregulated in the renal tubules of patients with AKI and cisplatin-treated mice

An update on the bridging factors connecting autophagy and Nrf2 antioxidant pathway

Van Campenhout et al

As shown in Figure 5E we observed a significant positive correlation between mitoSOX (gMFI) and FLICA (gMFI) in CD14 high CD16 monocytes from COVID-19 patients