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PatelDFPeirTShoemarkAAktharSWalkerSAGrabiecAMet alAn extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness

Glutathione can be administered orally, topically, or by injection (intravenous or intramuscular)

doi: 10.1002/jbmr.3951 70 FairfieldHDudakovicAKhatibCMFarrelMCostaSFalankC

Nat Genet 52:428436

Mutant presenilins 1 and 2 disrupt mitochondrial calcium signalling, which leads to decreased ATP production, increased ROS emission, and cell death [78]