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Human primary acute myeloid leukemia (AML) and metastatic liver cancer are characterized by significant elevation of the enzymes for glutathione biosynthesis, including GCL and GS (Pei et al , 2013

Lyme Disease & Co-Infections : These pathogens often trigger neurological symptoms and oxidative stress

Genome-wide CRISPR/Cas9 screening identifies CARHSP1 responsible for radiation resistance in glioblastoma

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Moreover, Cu toxicity not only resulted in deformed reproductive organs but also drastically reduced the GSI, fecundity, fertilization, and hatching rate of several fish species [18,21,133]

NRF2 is directly phosphorylated by protein kinase R-like ER kinase (PERK), a key mediator of the NRF2-HO-1 signaling pathway activation in response to erastin