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Committee on the Review of the Health Effects of Electronic Nicotine Delivery Systems, Board on Population Health and Public Health Practice, Health and Medicine Division, and National Academies of Sciences, Engineering, and Medicine

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It's about a mental disorder where by chance and happenstance dopamine pathway receptors have eight times greater affinity or attraction to nicotine than acetylcholine, the receptor's own neurotransmitter

By February 2020, the Centers for Disease Control and Prevention in the United States (CDC) had confirmed 68 deaths and reported more than 2,800 hospitalizations