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The overproduction of ROS may be decreased as a result of antioxidant supplementation, which may also enhance the quality of the semen and increase the likelihood of clinical pregnancy, live births, and decreased miscarriage rates (131)

By comparing with the normal human astrocyte cell line, the result of qRT-PCR and WB demonstrates that GPX8 was highly expressed in GBM cells, including LN-299, A172 and U251 ( Figure 8A )

Drawbacks include dose-dependent adverse effects and the development of steroid resistance

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