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Thirdly, the expression of Fas ligand (FasL) on tumor endothelial barrier selectively eliminates effector CD8 + T cells rather than Treg, due to the high expression of cellular FLICE-inhibitory protein (c-FLIP) expression on Treg [39]

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Specifically, quantitative analysis revealed that the relative average density (AOD) of CD31 was 1.48-fold higher in the G/D-CuP group than in the G/M-CuP group