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Many of these therapies have entered clinical trials, which are summarized in Table 2

doi: 10.1152/ajpcell.00542.2005 29 QiuJThapaliyaSRunkanaAYangYTsienCMohanMLet al

Of note, NAD + deficiency exerts effects on the emergence of oxidative stress in multiple diseases, while boosting NAD + has protective effects due to enhancement of antioxidant capacity via increasing the GSH levels and the activity of antioxidant enzymes

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