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PMID: 27770074, PMCID: PMC5123555, DOI: 10.1212/wnl.0000000000003353

Our CTC-based correlative studies demonstrate that effective therapeutic responses to the ARPI/BCL-2i combination in mCRPC patients may require concurrent suppression of AR and BCL-2 and clearance of CTCs whereas treatment resistance is marked by persistent CTC burden and associated with activation of alternative survival pathways such as GR

We therefore investigated the role of glutathione in intestinal barrier function and infection-induced mucosal inflammation

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SAP usually involves multiple organs, and its pathogenesis is associated with various factors, such as pancreatic enzyme activation, proinflammatory factors, and endotoxin release

Antioxidants capacity can be estimated by considering the final effects of their presence, by the use of in vitro tests, or directly by more complex methods utilizing exogenic probes to detect oxidation