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doi: 10.3389/fimmu.2025.1603658 Received 31 March 2025 Accepted 30 September 2025 Published 17 October 2025 Volume 16 - 2025 Edited by Vivek Verma, University of Minnesota Twin Cities, United States Reviewed by Tariq Ahmad Najar, New York University, United States Rena Feinman, Hackensack Meridian Health, United States Updates Copyright 2025 Lu, Yuan, Liang, Li, Jiang, Wang, Zhang and Liu