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RYDAPT is indicated for adult patients with newly diagnosed AML who are FLT3 mutation-positive, which would be similar to VANFLYTA's proposed patient population of adult patients with newly diagnosed AML that is FLT3-ITD positive

ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters

The reduced chromogen is directly proportional to GSH concentration and its absorbance measured at 405 nm using a commercial kit (Biodiagnostic, Egypt) (Noemann et al., 2011)

The GC-MS used was from Agilent (Palo Alto, CA, USA) and consisted of a 5977B mass spectrometer detector and a 7890B gas chromatograph

10.1098/rstb.2016.0154 Philos

Zhan, L