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GLP-1 receptor agonists Including semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) are peptide-based drugs that have completed full FDA review and carry approved indications for type 2 diabetes and obesity

Recent findings have hinted that any abnormality in these two opposing processes can influence the quantity and quality of mitochondria, which will further affect mitochondrial function and the ability of cells to adjust their mitochondrial networks in response to physiological adaptations and stress conditions (Palikaras et al., 2015

demonstrated that CRISPR/Cas9-mediated knockout of HIF-1 significantly enhances the antitumor efficacy of transarterial embolization (TAE) in hepatocellular carcinoma (HCC)

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Poole BD, Scofield RH, Harley JB, James JA

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