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Their principal advantages include dose-dependent estrogen suppression, fast reversibility of hormone secretion after treatment cessation, oral delivery, and avoidance of the flare-up effect

Symptoms may include: Skin rashes Itching Difficulty breathing Swelling of the face or throat If any severe allergic reaction occurs, immediate medical attention is necessary

Histidine itself has also been reported to have antioxidant properties, being a scavenger of free hydroxyl and singlet oxygen radicals and inhibiting fatty-acid oxidation during in vitro studies 51

Healthcare (Basel, Switzerland) , 9 (6), 671

And some antioxidants can help cells be more resilient to harmful free radicals (that can expedite aging processes)

Senescent chondrocytes accumulate in osteoarthritic joints, contributing to inflammation and tissue breakdown via the senescence-associated secretory phenotype (SASP)