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5 Treatment status and prospects IVDD is a leading cause of disability globally, imposing a substantial burden on both personal health and socioeconomic systems

After qPCR quantification using the KAPA library quantification kit (Roche), Sequencing was carried out on the NovaSeq 6000 instrument from Illumina based on a 2 100 cycle mode (paired-end reads, 100 bases) to obtain around 100 million clusters (200 million raw paired-end reads) per sample

The albumin acts as a circulating depot, slowly releasing active peptide

higher scores represent more active disease), an endoscopic subscore of 2, colonic involvement of 15 cm, and a confirmed diagnosis of ulcerative colitis for 3 months

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