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Slow hair growth, typically less than half an inch per month, can result from poor circulation and nutrient delivery to hair follicles

The method of reducing the single dose with the same total dose can make pharmacokinetics safer, lower trough concentration, and reduce the accumulation of cisplatin in the inner ear ( Pedmark, a sodium thiosulfate (STS) formulation, is the first and only novel drug approved by the US FDA to prevent the risk of cisplatin ototoxicity in children aged 1 month and older with localized non-metastatic solid tumors

Additionally, the Papot group developed a prodrug by combining a galactoside trigger with a folate receptor (FR) ligand, resulting in the tubulin inhibitor monomethyl auristatin E (MMAE) release (Legigan et al., 2012)

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Synnott NC, Madden SF, Bykov VJN, Crown J, Wiman KG, Duffy MJ

Omolaoye TS, du Plessis SS