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They looked at the results of 39 published studies, and determined there is significant evidence that two specific pathways for detoxification are impaired in autism, and that large trials are needed for children with autism to determine if boosting the function of these two pathways will likewise improve autistic behaviors

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Pregnant patients self-reported slightly fewer side effects like fever, headache and chills than the general population, but more said they experienced nausea and injection site pain

Due to the risk of respiratory depression with concomitant use of muscle relaxants and opioids, consider recommending or prescribing an opioid overdose reversal agent (see WARNINGS)

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