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Phase II pilot study of neoadjuvant docetaxel and cisplatin followed by adjuvant erlotinib in patients with resectable non-small cell lung cancer (NSCLC)

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Examining the pattern of change in these pathways at 4 and 8 h revealed the following patterns: two pathways remained upregulated (Lymphocyte Trafficking and Th2 Differentiation), three pathways reduced to the same level as control (Autophagy, Cell Adhesion, and Th1 Differentiation), and four were downregulated (Complement, Inflammasome, Type 1 IFN, and Type 2 IFN)

The full (liposome-encapsulated) peak plasma levels of doxorubicin in the non-modified PEGylated liposomes (Caelyx/Doxil) after a single intravenous injection of 6 mg/kg in rats were found to be stable for several hours (half-life was estimated to be about 24 hours), where GSH-modified PEGylated liposomes displayed a faster clearance resulting in an estimated half-life of 19 hours

[] Ellagic acid can prevent the PCa cells growth by stopping the cell cycle and stimulating apoptosis