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In parallel, genetic targeting approaches refine causal pathway analysis, including regulation of 5-hydroxytryptamine receptor 2B (Htr2b)-neuregulin 1 (Nrg-1)/erb-B2 receptor tyrosine kinase (ErbB) signaling (237), inhibition of inflammatory cascades through the XIST/miR-25-3p/TRAF3 axis (245) or the DEAD-box helicase 54 (DDX54)/MYD88/NLRP3 pathway (246), and suppression of pro-inflammatory signaling via the nuclear paraspeckle assembly transcript 1 (NEAT1)/miR-361-3p/TRAF2 network using triptolide (240)

However, a negative direct Coombs test in our patient could rule out autoimmune hemolytic anemia (AIHA)

76 Furthermore, during HBV infection, CD4 + T cells were shown to have essential roles on effector and memory CD8 + T-cell responses

Mice were placed on a rod, 30 mm in diameter, rotating at 4 rpm

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