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NNMT is overexpressed in select tissues (e.g., adipose tissue, skeletal muscle, etc.) in pathophysiological conditions, making it a clinically relevant target for drug development in several chronic diseases including obesity and diabetes

Liver disease : liver enzyme monitoring is recommended in community use, and a baseline ALT/AST check is reasonable before starting

Effective for Certain Conditions: Injections are often recommended for those with Crohns disease, celiac disease, or after gastric surgeries

Each option has distinct mechanisms, benefits, and limitations

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International journal of surgery case reports, 121, 109931