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A., Gokhale, N

Yang Y, Yu P, Lu Y, Gao C, Sun Q

doi: 10.1146/annurev-pathol-042220-023633 69

The mobile phase compositions were 0.1% trifluoroacetic acid (TFA) in water (A) and 0.1% TFA in CH3CN (B)

Studies have shown that IGF-1R can bind with the transcriptional coactivator of LEF1/TCF to upregulate the gene expression of cyclin D1 and axin2 (Warsito et al., 2012) and that it autoregulates its own gene expression (Sarfstein et al., 2012)