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3 A controlled trial of arbaclofen in 63 fragile X patients between 6 to 40 years of age has revealed significant beneficial treatment effects, such as improvements in socialization and social avoidance scores, particularly in those with more severe social impairments, suggesting that GABA B receptor agonists have potential to improve social function and behaviors in fragile X patients (Berry-Kravis et al., 2012)

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Unlike the highly specific targeting of infectious agents by adaptive immune responses, ROS and RNS exhibit indiscriminate toxicity toward biological systems through their capacity to react with lipid, amino acid, and nucleic acid moieties that are conserved among both eukaryotic host and invading microbe (Patel et al

Et comme pour les dangers de la vitamine D en excs, le fait quune vitamine soit hydrosoluble ou essentielle ne la met pas labri dun profil de risques propre

Forman et al., 2004)

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