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Data on study type (e.g., randomized controlled trial (RCT), randomized crossover trial, observational study), treatment parameters (e.g., dose, administration protocols, follow-up durations), patient characteristics (i.e., age, gender, symptom duration), AEs, and primary outcomes (as defined by study authors) were extracted

If you wont see at least 50% improvement then it may be best to consider other treatment options

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If the solution is not clear, it may be a sign of contamination or degradation, and we recommend not using it