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Several factors can potentially contribute to the final treatment outcome, including treatment adherence, tolerability, metabolic profile, and pre-existing health conditions of patients

Histamine Release: In the case of allergens being detected by your immune system, it releases histamines chemicals which cause the symptoms of allergies

You may have other underlying causes of premature graying or have additional nutritional deficiencies besides B12 deficiency (such as folic acid, iron, or pantothenic acid deficiency)

Werner, E., Ziegler, M., Lerner, F., Schweiger, M