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Notably, ximelagatran-induced DILI was only detected under chronic exposure conditions, mirroring clinical outcomes

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Symptoms of B12 Deficiency include: Weakness or fatigue Difficulty maintaining balance Cognitive difficulties, like memory loss Oral pain, especially a red or swollen tongue Tingling or numbness, especially in fingertips Distorted or blurred vision Dizziness or shortness of breath What to expect: Vitamin injections are quick and safe

By quantitatively varying attributes, all residues could be considered as allosteric residues because each residue senses the allosteric events. These maps could serve as fingerprints of allosteric consequences upon residue perturbation

Oncoimmunology 7:e1391972 Ellerby HM, Arap W, Ellerby LM, Kain R, Andrusiak R, Rio GD, Krajewski S, Lombardo CR, Rao R et al (1999) Anti-cancer activity of targeted pro-apoptotic peptides