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In addition to epigenetic and metabolic interventions, recent approaches have explored targeting the tumor microenvironment, inhibiting anti-apoptotic proteins (e.g., BCL2, MCL1), and utilizing immune checkpoint inhibitors in adaptive schedules

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Heterogeneous stain-ing of GPX1 in beta cells is consistent with recent obser-vations that demonstrate asynchronous destruction of beta cells during T1D (Thompson et al

10.1007/s00109-017-1575-8 23 ChrysohoouC.KolliaN.TousoulisD

doi: 10.3390/pharmaceutics14051079 20 CordeiroD.SternT.SternS