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Notably, in this study, vitamin D appears to influence the development of pulmonary fibrosis through multiple biological pathways: vitamin D deficiency not only exacerbates the lung inflammation caused by bleomycin (similar to the effect observed in the case of vitamin C deficiency), but also increases the likelihood of the occurrence of EMT in the lungs, and these are all crucial steps in the pathogenesis of pulmonary fibrosis

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However, using variants that do not dimerize, it has been recently described that homodimer formation of GCL is not required for enzyme activation (Yang et al., 2019)

These are very small brown spots that may appear in the iris of the eye

Role of autophagy and apoptosis in non-small-cell lung cancer

Liu R, Guo C, Feng M, Liu CZ (2021) Efficient microwave-assisted extraction of salidroside from Rhodiola crenulata