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Thus, it has been suggested that certain inflammatory markers can be used as biomarkers for PTSD (Cohen et al., A study conducted on Iraq and Afghanistan deployed US-veterans under the age of 55 that were associated with PSTD and endocrine and immune abnormalities reported increased risk for developing autoimmune diseases such as MS, rheumatoid arthritis, thyroiditis, lupus erythematosus, and inflammatory bowel disease (IBD) (O'donovan et al., 2015)

TTA was expressed as the amount (mL) of 0.1 M NaOH needed to reach a pH value of 8.3

2 moles of pyruvate are formed per mole of glucose In cells with mitochondria and oxidative metabolism, pyruvate is converted completely into CO 2 and H 2 O glycolysis in this setting is termed aerobic glycolysis

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doi: 10.1038/d41586-022-00104-8 3 LiCXNoreenSZhangLXSaeedMWuPFIjazMet al

Indeed, in the human body, ROS are mainly produced in mitochondria, peroxisomes, and the endoplasmic reticulum, being continuously generated by enzymatic reactions that involve cyclooxygenases, NADPH and xanthine oxidases, and lipoxygenases and through the Fenton reaction [7]