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Del Giudice, M

[24] Type 2 Diabetes Inflammation (along with oxidative stress) plays a crucial role in the development of insulin resistance and type 2 diabetes

The compound's effects are mechanistically downstream from its presenceit initiates biological processes that continue autonomously after plasma clearance

Nzory na tuto ltku se ve studich i terapeutickch standardech rozchzej, a zatmco proveden metaanalzy [20, 21] jej innost spe potvrzuj, nkter z aktulnch guidelines nedoporuuj kyselinu -lipoovou u DPN pro nedostatek dkaz [22].Vzhledem k tomu, e je CIPN nedoucm inkem aplikace liv, lze rozdlit pouvan liva na dv skupiny ltky pro prevenci vzniku a rozvoje CIPN a standardn symptomatickou lbu CIPN

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Finkel T., Holbrook N.J

73 demonstrated that exercise for 3 weeks increased eNOS and extracellular SOD protein levels in wild-type mice but had no effect on extracellular SOD protein levels in eNOS-knockout mice and that the effect of endothelium-derived NO on extracellular SOD protein level is mediated by the cGMP/protein kinase G-dependent pathway