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bFGF, which is one of the 22 different isotypes of FGF, plays a crucial role in the wound healing process by promoting fibroblast proliferation, inducing neovascularization, and increasing the synthesis of collagenase.3033 As the topical administration of human recombinant bFGF has been shown to be effective for wound healing in clinical situations, we selected bFGF as a positive reagent in this study

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5-Amino-1MQ is a small-molecule quinolinium compound not a peptide that selectively inhibits nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme involved in the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor

Store reconstituted solution in amber vials or wrapped in foil

Br Med J 1991;302:749-52