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Their expression was validated in bulk RNA-seq datasets

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It partially reversed stroke-induced intestinal barrier disruption and leakage, inflammation, dyslipidemia and oxidative stress, as well as the stroke-induced increase in pathogenic gut microbiota (e.g., Escherichia-Shigella , Enterococcus, Clostridium_innocuum_group ) and decrease in beneficial microbiota (e.g., Lachnospiraceae , unclassified__f__Lachnospiracea and Ruminococcus_torques_group )