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PDG2 and its conversion product 15d-PGJ2 are neuroprotective by reducing NF-B activation, decreasing proinflammatory genes and by activating the transcription factor PPARgamma (45)

-J., Murphy, M

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In particular, Serhan and colleagues identified new families of potent anti-inflammatory lipid mediators derived from omega-3 fatty acid, called specialized pro-resolving mediators (SPMs), which include resolvins, neuroprotectin, and maresins (Serhan et al., 2002

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The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death