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Age-related muscle loss (the progressive loss of skeletal muscle mass and strength) may increase the risk of falls and has been associated with increased mortality (Clynes, Calcif Tissue Int 2015)

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Genes 2(12):11171133 Olsson A-K et al (2006) VEGF receptor signalling

Diagnosis typically involves B12 level testing, intrinsic factor antibody tests, and sometimes specialized absorption studies like the Schilling test

The N -terminal domain is the hinge-like domain that intertwines between the two subunits and contributes to the stability of the dimer structure