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cerevisiae have been identified as manganese-dependent superoxide dismutase (Mn-SOD) and copper, zinc-dependent superoxide dismutase (Cu, Zn-SOD)

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Search strategy We systematically searched the five electronic databases, MEDLINE, Embase, CINHAL, Web of Science, and Google Scholar, for publications and the CENTRAL Cochrane Library trial registry for ongoing and terminated trials from inception to April 5, 2022, and updated the search on November 14, 2023

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All SAEs will be followed up until satisfactory resolution or until the treating physicians and the principal investigator deem the event to be chronic or the participant to be stable