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Long-term safety in humans remains under investigation

In a LPS-induced model of acute lung injury in male septic mice, the metabolism of choline/L-carnitine by gut microbiota is reprogrammed

8 Studies Analyzed Carnitine Carnitine can carry long-chain fatty acids to cell mitochondria to be broken down for energy and converted to ATP

10.1016/j.neuint.2017.06.006 97 ProzorovskiT.Schulze-TopphoffU.GlummR.BaumgartJ.SchrterF.NinnemannO.et al (2008)

Unlike in lymph node targeting strategies, most approaches for enhancing GALT delivery rely on oral administration, which is complicated by physiological barriers of the digestive system resulting in nanoparticle degradation or excretion (120)