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Finally, phosphorylation of S377 on AMPK2 associated with glucose uptake in insulin-stimulated and/or exercised skeletal muscle from individuals with differing muscle insulin sensitivity, and was necessary for proliferation of MEF cells during glucose deprivation, suggesting a regulatory role in glucose metabolism [35]

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[352] It plays a role in regulating intraocular pressure in the eye through its potential complex interaction with nitric oxide, a crucial signaling molecule affecting blood vessel dilation

Exposing murine pancreatic -cells to pro-inflammatory cytokines IL-6 and IL-1 led to changes in the cell metallome, especially a decrease in Zn and Ca content and an increase in Fe content, together with changes in the cellular distribution of these metals

Avoid Smoking and Alcohol Smoking and heavy drink use lower glutathione levels

Chemical Information Appearance Solid Molecular Weight 258.77 Formula C 8 H 19 ClN 2 O 3 S Color White to off-white SMILES N[C@H](C(O)=O)CCS(CCCC)(=O)=N.[H]Cl Synonyms L-Buthionine sulfoximine hydrochloride