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The targeted approach refers to quantitation of chemically annotated metabolites using isotope labeling

Numerous studies to date have demonstrated the antitumor effect of vitamin C in a variety of malignancies

[Epub ahead of print] Decramer M, Janssens W, Miravitlles M

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Feingold KR, Adler RA, Ahmed SF, et al., editors

In another study, glycolytic enzyme enolase 1 (ENO1), and in turn glycolysis, were increased in cisplatin resistant gastric cancer cells, which could be targeted by the glucose analog 2-DG (Qian et al., 2017)