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Patil A, Goldust M, Wollina U

75 GundersenV.OttersenO

SPR experiments demonstrate that while the pHAT domains in eukaryotic OGAs retain a putative acceptor binding site, they cannot bind acetyl-CoA, classifying them as pseudo-histone acetyl transferases

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Protection Against Anti-Drug Antibodies (Immunogenicity): This is one of the most important reasons MTX remains the anchor when biologic therapies are introduced

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