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Until dedicated trials are available, the use of GLP-1RAs in AITD should be viewed as an intriguing but unproven strategy, one that underscores the evolving interface between metabolism, immunity, and endocrine care

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It utilized inducible cell lines for initial validation, corroborated relevance in ex vivo and knockout models, and finally interrogated the underlying mechanisms using brain slice electrophysiology and pharmacology

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Serotonin release was blunted following d-amphetamine administration, as measured by changes in displacement of a 5HT-2A agonist radiotracer [83]

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