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Williams 82) and the Gmmorf2a/b mutants were maintained at 22 C in a growth chamber with a 16 h day/8 h night cycle (100150 mol photons m 2 s 1 )

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Sparc is a source of copper-binding peptides that stimulate angiogenesis

Endothelial cells from injured muscle are known to secrete TNF-, IL-1, IL-6 and IL-8, providing a positive feed-forward cycle (290, 298)

) as standard for 21 days (starting from 3rd day)

This idea was already proposed when two patients treated with RNA-electroporated TCR-T cells experienced clear shrinkage of the primary tumor [53,54] or metastases [13]