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Description

TREX1 dictates the immune fate of irradiated cancer cells

The overexpression of HIC1 markedly enhanced the inhibition of GPX4 expression and promoted ferroptosis

Extracts were shaken at 150 rpm for 12 h and the powder was allowed to settle

This modification appears early in the G2 phase within pericentromeric heterochromatin and spreads, coinciding with mitotic chromosome condensation

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This primary composite outcome of death or severe neurodisability was more frequent in males than females, with more male deaths or survival with impairment, in particular those treated with indomethacin (100)