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Additional research also suggests that diabetic patients treated with exenatide may have a reduced risk of developing PD [132]

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In the IRI model, elevated expression of the E3 Ub-protein ligase HMG-CoA reductase degradation protein 1 (HRD1) increases ubiquitinated degradation of the -catenin degradation complex, stabilizes -catenin proteins, and thereby enhances Wnt / -catenin signaling[50]

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4.1 Pro-tumor immune mechanisms of LECs Basic mechanism through which LECs can directly promote tumor cell migration and invasion is by providing a route for cancer cells to enter the LVs and disseminate to distant sites (78, 97) ( Figure 3A )

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In this study, we have experimentally demonstrated that glutathione loss-triggered oxidative stress can induce neurodegeneration, and that neuroinflammation plays an important role in the process of oxidative stress-induced neurodegeneration

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